Which endogenous ligand is primarily associated with mu receptors?

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Multiple Choice

Which endogenous ligand is primarily associated with mu receptors?

Explanation:
Mu receptors are most strongly activated by endorphins, especially beta-endorphin. Endorphins have the highest affinity for mu receptors and mediate analgesia and feelings of euphoria. Enkephalins primarily target delta receptors (with some mu affinity), dynorphins prefer kappa receptors, and Substance P is a non-opioid neuropeptide involved in pain signaling. So the endogenous ligand most closely associated with mu receptors is endorphins.

Mu receptors are most strongly activated by endorphins, especially beta-endorphin. Endorphins have the highest affinity for mu receptors and mediate analgesia and feelings of euphoria. Enkephalins primarily target delta receptors (with some mu affinity), dynorphins prefer kappa receptors, and Substance P is a non-opioid neuropeptide involved in pain signaling. So the endogenous ligand most closely associated with mu receptors is endorphins.

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