Propofol is metabolized by which sites?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $9.99Unlock all

Prepare for the Anesthesia Pharm Exam with our comprehensive study resources. Utilize flashcards and detailed multiple-choice questions complete with hints. Ace your exam and become proficient in anesthesia pharmacology!

Multiple Choice

Propofol is metabolized by which sites?

Explanation:
Propofol is cleared by metabolism primarily in the liver, where it is conjugated and hydroxylated to inactive metabolites. A meaningful portion is also metabolized outside the liver in extrahepatic tissues, especially the lungs, due to their high perfusion and metabolic activity. So the sites of metabolism are the liver and other tissues beyond the liver. Lungs alone would miss the liver’s major role, and brain or kidney alone don’t capture the established pattern of propofol metabolism.

Propofol is cleared by metabolism primarily in the liver, where it is conjugated and hydroxylated to inactive metabolites. A meaningful portion is also metabolized outside the liver in extrahepatic tissues, especially the lungs, due to their high perfusion and metabolic activity. So the sites of metabolism are the liver and other tissues beyond the liver. Lungs alone would miss the liver’s major role, and brain or kidney alone don’t capture the established pattern of propofol metabolism.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy