Meperidine releases histamine to a greater extent than morphine, which can cause which effect at high doses?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $9.99Unlock all

Prepare for the Anesthesia Pharm Exam with our comprehensive study resources. Utilize flashcards and detailed multiple-choice questions complete with hints. Ace your exam and become proficient in anesthesia pharmacology!

Multiple Choice

Meperidine releases histamine to a greater extent than morphine, which can cause which effect at high doses?

Explanation:
Meperidine releases histamine from mast cells more than morphine, and histamine causes vasodilation of peripheral vessels. This vasodilation lowers systemic vascular resistance and falls in blood pressure occur, especially at higher histamine release. So the primary hemodynamic effect is hypotension. Reflex tachycardia can accompany the drop in pressure, but the direct and most notable change with high-dose histamine release is reduced blood pressure.

Meperidine releases histamine from mast cells more than morphine, and histamine causes vasodilation of peripheral vessels. This vasodilation lowers systemic vascular resistance and falls in blood pressure occur, especially at higher histamine release. So the primary hemodynamic effect is hypotension. Reflex tachycardia can accompany the drop in pressure, but the direct and most notable change with high-dose histamine release is reduced blood pressure.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy